Sputnik V produces a better neutralizing antibody response to Omicron than the mRNA vaccines, Professor Hildegund Ertl, one of the top US vaccine specialists, said, according to a statement posted on Sputnik V Twitter page on Monday.
The vaccine and immunotherapy researcher working at the Wistar Institute located in Philadelphia, Pennsylvania, believes that the Russian jab’s adenoviral vector provides for a “far longer” expression of antigen than any of the mRNA vaccines. This results in “stimulation of durable antibody-secreting cells,” the statement said.
“Overall, these results are extremely promising,” professor Ertl said while commenting on the results of a fresh comparative study presented by a joint Russian-Italian team working at the Spallanzani Institute, Italy’s leading research institute for infectious diseases. The team published a preprint of the study last week.
The researchers at the Spallanzani Institute studied the serum samples from individuals vaccinated with Sputnik V and Pfizer and found that the Russian jab produces twice as high level of virus neutralizing antibodies against Omicron as the US vaccine, which, in turn, means better protection against the virus.