Scientists from Lancaster University in the UK found that the drug for treating diabetes can be used to combat age-related diseases, including Alzheimer’s disease. Article researchers published in the journal Brain Research. About it reported in a press release on EurekAlert!.
In the experiment, we used transgenic mice, in which DNA there was a gene responsible for the development of Alzheimer’s disease in humans. At the late stage of neurodegeneration in an organism of animals were administered triple-drug-containing analogs of growth factors (GLP-1, GIP and glucagon) — compounds that stimulate the development of tissues. With the disease of Alheimer in the human brain there is a shortage of these compounds.
The results showed that the drug reduced the number of plaques in the brain of rodents and also reduced the level of inflammation and oxidative stress, which slows the loss of nerve cells.
Researchers from the Mayo clinic and the Center for the study of Alzheimer’s disease proved that physical exercise can slow the aging and related deterioration of the brain. It is shown that exercise improves memory and other cognitive functions in older people, and also stop the development of age-related neurodegenerative diseases.
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