Special chemical compounds are able to resist the spread of bacterial infection, American scientists have found.
To cause infection, bacteria must be fixed in certain places of the body of the host and begin to multiply to form biofilm.
Previous studies of the group of chemists and biochemists from Worcester Polytechnic Institute and the University of Massachusetts showed that cranberry juice contains bioactive ingredients called “proanthocyanidins”. These compounds belong to the flavonoids — plant pigments that affect the color of flowers and fruits of plants. Experiments have shown that proanthocyanidins inhibit the ability of bacteria to attachment to the body of the host.
A new study conducted by a group led by Professor Terry Camesano (Terri Camesano), have shown that cranberry juice contains a class of flavonoids — flavonols. These substances as well as proanthocyanidins, effectively help prevent the onset of bacterial infection, as they reduce the ability of bacteria to attach to any surface. In particular, we are talking about bacteria Escherichia coli(E. coli), different strains of which are responsible for the development of many infectious diseases, including urinary tract infections. It should be noted that in folk medicine, cranberry juice is usually recommended to apply it with this type of infection.
“We believe that contained in cranberry juice, flavonols, and proanthocyanidins, are part of the protective system of the plant, — said one of the authors of the study, Catherine Neto (Catherine Neto). — These substances begin to stand out in high concentrations when the plant is attacked by pathogenic bacteria”.
Based on these data, scientists believe that cranberry juice can become in future the basis for the development of alternative methods of treatment of bacterial infections. Antimicrobial properties of compounds in the juice, should be sent to fight resistant to antibioticbactrim, the researchers believe.
Today, scientists of all countries looking for a way to deal with antimicrobial resistance and inventing new drugs. For example, researchers from Rutgers University has proposed to combine an experimental drug with an existing one, and scientists from the University of Colorado has invented a drug based on nanoparticles.
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