“Science film” contains only one scene.
Biologists from Harvard University in the US encoded in the DNA of Escherichia coli animation of the running horse designed by Edward Meybridzha in the nineteenth century. For this purpose, the researchers used a technology called CRISPR/Cas9 to insert into the bacterial genome nucleotides, which correspond to the components of the image pixels. Reading of DNA sequence has allowed to reproduce the video with 90% accuracy. Article scientists published in the journal Nature.
The CRISPR/Cas system can be used to alter the nucleotide DNA sequence. Cas9 is a protein that cuts double chain in a particular area. This place defines guide RNA (trnk), which binds to a specific site of recognition by the principle of complementarity. Various drnk coded spacers — stretches of DNA within a CRISPR — group special repeated sequences.
Bacterium gets spacers in a natural way, by borrowing from pathogenic viruses fragments of their own DNA, called protosphere. After the fragment was integrated into the CRISPR, procaspase becomes a sign, allowing the microorganism to recognize the infection through drink.
First, scientists used this technology to record in the DNA image of the hand during each of the 21 colors of the pixels has been encoded in the nucleotide sequence of the synthetic protospatharios. The latter was introduced into bacterial cells, each of which had a functional CRISPR enzyme complex and Cas1-Cas2 to create a new spacers based on protospatharios.
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