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Scientists have discovered how alcohol causes damage to DNA

Ученые выяснили, как алкоголь повреждает ДНКAlcohol damages DNA of cells-precursors cerveobraznae cells, scientists have found.

This increases the risk of developing cancer.

The researchers gave the mice a solution of ethanol, and then analyzed the DNA of stem cells. Blood cells were used, in particular, because the damage he caused spreads to the entire body.

As it turned out, acetaldehyde, a breakdown product of ethanol, can cause double-stranded breaks in DNA. In addition, genetically modified mice incapable of developing breaks down acetaldehyde of enzymes, DNA damage was four times more.

The body is protected from exposure to acetaldehyde in two ways, the researchers explain. First, with the help of a group of enzymes, acetyldihydrocodeine turns acetaldehyde to acetate, which can use for energy.

Secondly, try to repair damaged DNA. However, some people (especially among Asians) congenital mutations lead to the fact that none of these protection systems is not working, which greatly increases the risk of cancer, particularly esophageal cancer, scientists warn.

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