Scientists in more than 1.4 thousand swine embryos injected one of three types of human induced pluripotent stem cells.
Biologists from the United States, Spain and Japan have created chimeras — hybrids of pigs and humans. A study first published in the journal Cell.
Hybrids were obtained in the following way. Scientists in more than 1.4 thousand swine embryos injected one of three types of human induced pluripotent stem cells. Then the embryos were transplanted into sows, where they developed successfully. Tracking the dynamics of human material was conducted using a fluorescent protein, production of which has been programmed human stem cells.
In the end, the last in the pig embryo formed cells, which are precursors of various tissues, especially the heart, liver and nervous system. Hybrids pigs and humans have allowed to develop within three to four weeks, after which for ethical reasons they were destroyed.
The ultimate goal of their experiments, the scientists see the development of effective methods of growing organs suitable for subsequent transplantation to a patient.
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